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Microwave assisted synthesize of new some benzimidazole derivatives and determination of protonation constant of these compounds in non-aqueous media

, Fatih İslamoğlu, Esra Bal,
European Journal of Chemistry , Volume 4, pp 25-28; doi:10.5155/eurjchem.4.1.25-28.729

Abstract: A series of 2-substituted benzimidazole derivatives have been synthesized via microwave mediated process. Different benzimidazole derivatives were titrated with tetrabutylammonium hydroxide in four non-aqueous solvents (isopropyl alcohol, N,N-dimethylformamide,tert-butyl alcohol and acetonitrile), using potentiometric method. The half neutralization potential values and the corresponding pKa values were determined for all cases.
Keywords: benzimidazole derivatives / alcohol / TERT / acetonitrile / Corresponding Pka Values / cited / Assisted Synthesize / Microwave assisted

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