Unusual appearances of COVID-19 (2019 novel corona virus) infected persons. The early epicenter of the pandemic, Wuhan, China has obtained medical and scientific information and knowledge in response to the infection of COVID-19. On thirteen case series and nine case-based reports, I want to put five significant facts of ophthalmic indicators of COVID-19 infected persons, hopefully, to deliver the fresh view as well as a wider perspective of COVID-19 infection.