LC-MS/MS Method for the Quantitative Determination of Tanespimycin and its Active Metabolite in Human Plasma: Method Validation and Overcoming an Insidious APCI Source Phenomenon

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[icon name="unlock"] OPEN-ACCESS [icon name="eye"] PEER-REVIEWED ORIGINAL RESEARCH Morse Faria1,*, Omnia A. Ismaiel1,2, James Waltrip1, Tom Mariannino1, Moucun Yuan1, William... This paper describes a validated method to simultaneously measure tanespimycin and its active metabolite in human plasma by LC-MS/MS.