Identification of novel translated small ORFs in Escherichia coli using complementary ribosome profiling approaches

Abstract
Small proteins of Escherichia coli cells treated with antibiotics that stall ribosomes at either start or stop codons. Thus, we identify ribosome-occupied start and stop codons for ~400 novel putative ORFs with high sensitivity. The newly discovered ORFs are mostly short, with 365 encoding proteins of Escherichia coli.
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