Prosthetic rehabilitation of a patient with X-linked hypophosphatemia using dental implants: a case report and review of the literature
Open Access
- 22 April 2019
- journal article
- review article
- Published by Springer Science and Business Media LLC in International Journal of Implant Dentistry
- Vol. 5 (1), 15
- https://doi.org/10.1186/s40729-019-0169-3
Abstract
X-linked hypophosphatemia is associated with a range of dental problems, many of which may result in early loss of the dentition. Most patients, but especially young adults, are likely to desire fixed prosthodontic replacements, and dental implants may be the preferred solution in many cases. The use of dental implants to rehabilitate this patient group has not been widely studied with the literature limited to a small number of case reports with limited follow-up. This case report describes the dental journey of a young adult with X-linked hypophosphatemia, his eventual tooth loss and rehabilitation with multiple dental implants. Over 10 years’ follow-up of three of the fixtures is presented. This case report shows a common presentation and progression of a patient with X-linked hypophosphatemia and will hopefully provide further positive evidence for the clinician to rely on when considering dental implant based treatments for such patients.Keywords
This publication has 43 references indexed in Scilit:
- MEPE-Derived ASARM Peptide Inhibits Odontogenic Differentiation of Dental Pulp Stem Cells and Impairs Mineralization in Tooth Models of X-Linked HypophosphatemiaPLOS ONE, 2013
- Novel and de novo PHEX mutations in patients with hypophosphatemic ricketsBone, 2013
- Tooth dentin defects reflect genetic disorders affecting bone mineralizationBone, 2012
- Periapical and endodontic status of permanent teeth in patients with hypophosphatemic ricketsJournal of Oral Rehabilitation, 2011
- A clinician's guide to X-linked hypophosphatemiaJournal of Bone and Mineral Research, 2011
- Familial hypophosphatemic vitamin D–resistant rickets—prevention of spontaneous dental abscesses on primary teeth: A case reportOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2009
- Dentin structure in familial hypophosphatemic rickets: benefits of vitamin D and phosphate treatmentOral Diseases, 2007
- Coordinated Maturational Regulation of PHEX and Renal Phosphate Transport Inhibitory Activity: Evidence for the Pathophysiological Role of PHEX in X-Linked HypophosphatemiaJournal of Bone and Mineral Research, 1999
- Oral findings in patients with autosomal dominant hypophosphatemic bone disease and X-linked hypophosphatemia: Further evidence that they are different diseasesOral Surgery, Oral Medicine, Oral Pathology, 1988
- Electron optic analysis of human dentin in hypophosphatemic vitamin D-resistant rickets (Report of a kindred with consanguinity)Journal of Oral Pathology & Medicine, 1973