Intradialytic exercise improves physical function and reduces intradialytic hypotension and depression in hemodialysis patients
Open Access
- 1 May 2019
- journal article
- research article
- Published by Korean Association of Internal Medicine in The Korean Journal of Internal Medicine
- Vol. 34 (3), 588-598
- https://doi.org/10.3904/kjim.2017.020
Abstract
Background/Aims: As numbers of maintenance hemodialysis patients are growing, debilitating conditions of muscle wasting and atrophy are becoming some of the greatest concerns in end-stage renal disease patients. Exercise training has various potential benefits in terms of prevention of a sustained decline in functional status. This study aimed to evaluate the physical, psychological, laboratory, and dialysis-related effects of intradialytic exercise. Methods: We enrolled 22 patients from a hemodialysis center for a 6-month nonrandomized prospective trial. Combination of aerobic exercise with bicycle ergometer and anaerobic exercise with elastic bands was conducted during hemodialysis. Data including physical fitness test results, dialysis-related measurements, and biochemical laboratory results were collected at baseline, 3, and 6 months. Depression and quality of life were assessed using Beck Depression Inventory and Short Form-36 health survey. Results: After exercise completion, there were significant improvements in back muscle power, forward and backward trunk flexibility, vertical jump, elbow flexion, sit to stand test, and 6-minute walk test (p < 0.05). No significant changes were observed in dry weight, blood pressure, Kt/V, and biochemical variables, except for intradialytic hypotension (p < 0.05). For depression, Beck Depression Inventory showed statistically significant enhancement (p < 0.05). Scores of Short Form-36 health survey did not show significant increase in each domain, except for bodily pain (p < 0.05). Conclusions: Combined aerobic and anaerobic exercise training during dialysis was found to be effective on physical health status, intradialytic hypotension, and depression in terms of mental health. Therefore, the findings of the current study may provide an appropriate guidance for encouraging exercise by nephrologists.Keywords
Funding Information
- Korean Society of Nephrology
This publication has 40 references indexed in Scilit:
- Efficacy of Muscle Exercise in Patients with Muscular Dystrophy: A Systematic Review Showing a Missed Opportunity to Improve OutcomesPLOS ONE, 2013
- Attenuated Cardiovascular Response to Sympathetic System Activation during Exercise in Patients with Dialysis-Induced HypotensionAmerican Journal of Nephrology, 2011
- Effect of Intradialytic Resistance Band Exercise on Physical Function in Patients on Maintenance Hemodialysis: A Pilot StudyJournal of Renal Nutrition, 2011
- Intradialytic Exercise Programs for Hemodialysis PatientsChonnam Medical Journal, 2011
- Functional Status of Elderly Adults before and after Initiation of DialysisThe New England Journal of Medicine, 2009
- Intradialytic Parenteral Nutrition Does Not Improve Survival in Malnourished Hemodialysis PatientsJournal of the American Society of Nephrology, 2007
- ForewordAmerican Journal of Kidney Diseases, 2005
- Exercise capacity as a predictor of survival among ambulatory patients with end-stage renal diseaseKidney International, 2004
- Decreased survival among sedentary patients undergoing dialysis: Results from the dialysis morbidity and mortality study wave 2American Journal of Kidney Diseases, 2003
- Psychological Effects of Exercise Training in Hemodialysis PatientsNephron, 1983