Alzheimer’s Disease and COVID-19 fatalities linked to the NLRP3 inflammasome overregulation

Abstract

The aim of this work is centered on the people living in the two most populated cities in the Canary Islands. Spain, which was motivated by the observed peak of COVID-19 severe patients; and fatalities in Santa Cruz de Tenerife more than in Las Palmas de Gran Canaria over the first COVID wave. It is suggested here that this fact was due to a huge African dust storm in February 2020 during the popular Carnival festivity that was not cancelled following the Government indications for people to stay at home, contrary to other islands that obeyed the objection. Also, in the second wave, the number of cases is much higher in Santa Cruz de Tenerife as well, following the same behavior rules of coexistence for citizens in all the seven major islands. We also analyzed the incidence and mortality due to AD