Feasibility study of fiducial marker localization using microwave radar
- 4 September 2021
- journal article
- research article
- Published by Wiley in Medical Physics
- Vol. 48 (11), 7271-7282
- https://doi.org/10.1002/mp.15197
Abstract
Purpose: We explore the potential use of radar technology for fiducial marker tracking for monitoring of respiratory tumor motion during radiotherapy. Historically microwave radar technology has been widely deployed in various military and civil aviation applications to provide detection, position and tracking of single or multiples objects from far away and even through barriers. Recently, due to many advantages of the microwave technology, it has been successfully demonstrated to detect breast tumor, and to monitor vital signs in real-time such as breathing signals or heart rates. We demonstrate a proof-of-concept for radar-based fiducial marker tracking through the synthetic human tissue phantom. Methods: We performed a series of experiments with the vector network analyzer (VNA) and wideband directional horn antenna. We considered the frequency range from 2.0 to 6.0 GHz with a maximum power of 3 dBm. A horn antenna, transmitting and receiving radar pulses, was connected to the vector network analyzer to probe a gold fiducial marker through a customized synthetic human tissue phantom, consisting of 1-mm thickness of skin, 5-mm fat, and 25-mm muscle layers. A 1.2 x 10-mm gold fiducial marker was exploited as a motion surrogate which was placed behind the phantom and statically positioned with an increment of 12.7-mm to simulate different marker displacements. The returned signals from the marker were acquired and analyzed to evaluate the localization accuracy as a function of the marker position. Results: The fiducial marker was successfully localized at various measurement positions through a simplified phantom study. The averaged localization accuracy across measurements was 3.5 ± 1.3 mm with a minimum error of 1.9 mm at the closest measurement location and a maximum error of 4.9 mm at the largest measurement location. Conclusion: We demonstrated that the 2-6 GHz radar can penetrate through the attenuating tissues and localize a fiducial marker. This successful feasibility study establishes a foundation for further investigation of radar technology as a non-ionizing tumor localization device for radiotherapy. This article is protected by copyright. All rights reservedKeywords
This publication has 42 references indexed in Scilit:
- Microwave tomography: review of the progress towards clinical applicationsPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2009
- Exhale fluctuation in respiratory-gated radiotherapy of the lung: A pitfall of respiratory gating shown in a synchronized internal/external marker recording studyRadiotherapy and Oncology, 2008
- Fluoroscopic tracking of multiple implanted fiducial markers using multiple object trackingPhysics in Medicine & Biology, 2007
- Real-time intra-fraction-motion tracking using the treatment couch: a feasibility studyPhysics in Medicine & Biology, 2005
- Real‐time tumor‐tracking radiation therapy for lung carcinoma by the aid of insertion of a gold marker using bronchofiberscopyCancer, 2002
- Model Selection and the Principle of Minimum Description LengthJournal of the American Statistical Association, 2001
- The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissuesPhysics in Medicine & Biology, 1996
- The dielectric properties of biological tissues: II. Measurements in the frequency range 10 Hz to 20 GHzPhysics in Medicine & Biology, 1996
- Irradiation synchronized with respiration gateInternational Journal of Radiation Oncology*Biology*Physics, 1989
- Model selection and Akaike's Information Criterion (AIC): The general theory and its analytical extensionsPsychometrika, 1987