Norepinephrine in Chronic Paranoid Schizophrenia: Above-Normal Levels in Limbic Forebrain
- 28 April 1978
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 200 (4340), 456-458
- https://doi.org/10.1126/science.644310
Abstract
In postmortem examination of brains of four patients with chronic paranoid schizophrenia, above-normal norepinephrine levels were measured in the ventral septum, the bed nucleus of the stria terminalis, the nucleus accumbens, and the mammillary bodies. No changes were detected in other limbic forebrain regions, including the hypothalamus and the medial olfactory (preoptic) area. The results point to the possibility of a malfunction of limbic noradrenergic mechanisms in schizophrenia, especially the paranoid variety.This publication has 32 references indexed in Scilit:
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