Cognitive Impairment during High-Intensity Exercise: Influence of Cerebral Blood Flow
- 11 October 2019
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Medicine & Science in Sports & Exercise
- Vol. 52 (3), 561-568
- https://doi.org/10.1249/mss.0000000000002183
Abstract
Thesis that a reduction in CBF is responsible for impaired cognitive performance during high-intensity exercise. Methods Using a randomized crossover design 17 healthy males performed spatial delayed response and Go/No-Go tasks in three conditions (exercise [EX], exercise+CO2 [EX+CO2], and a nonexercising control [CON]). In the EX and EX+CO2, they performed cognitive tasks at rest and during 8 min of moderate and high-intensity exercise. Exercise intensity corresponded to ~50% (moderate) and ~80% (high) of peak oxygen uptake. In the EX+CO2, the participants inspired hypercapnic gas (2% CO2) during high-intensity exercise. In the CON, they performed the cognitive tasks without exercise. Results Middle cerebral artery mean velocity increased during high-intensity exercise in the EX+CO2 relative to the EX (69.4 [10.6] cm·s−1, vs 57.2 [7.7] cm·s−1, P < 0.001). Accuracy of the cognitive tasks was impaired during high-intensity exercise in the EX (84.1% [13.3%], P < 0.05) and the EX+ CO2 (85.7 [11.6%], P < 0.05) relative to rest (EX: 95.1% [5.3%], EX+CO2: 95.1 [5.3%]). However, no differences between the EX and the EX+CO2 were observed (P > 0.10). These results demonstrate that restored CBF did not prevent cognitive impairment during high-intensity exercise. Conclusions We conclude that a reduction in CBF is not responsible for impaired cognitive performance during high-intensity exercise....This publication has 39 references indexed in Scilit:
- The Effects of Exercise Under Hypoxia on Cognitive FunctionPLOS ONE, 2013
- Cerebrovascular ReserveExercise and Sport Sciences Reviews, 2012
- Does cerebral oxygen delivery limit incremental exercise performance?Journal of Applied Physiology, 2011
- Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy AdultsMedicine & Science in Sports & Exercise, 2011
- Catecholamine Influences on Dorsolateral Prefrontal Cortical NetworksBiological Psychiatry, 2011
- Cerebral blood flow and oxygenation at maximal exercise: The effect of clamping carbon dioxideRespiratory Physiology & Neurobiology, 2011
- Acute incremental exercise, performance of a central executive task, and sympathoadrenal system and hypothalamic-pituitary-adrenal axis activityInternational Journal of Psychophysiology, 2009
- Cerebral Blood Flow Response to Functional ActivationJournal of Cerebral Blood Flow & Metabolism, 2009
- Elevation in cerebral blood flow velocity with aerobic fitness throughout healthy human ageingJournal Of Physiology-London, 2008
- On the relationship between emotion and cognitionNature Reviews Neuroscience, 2008