This paper examined how political elites have excluded a number of people from partisan politics, and discussed the effect of the domineering role of political elites on good governance in Oyo state, Nigeria. The paper also examined the challenges that politics of exclusion pose on good governance in the study area. The study adopted primary and secondary data. For the primary data, in-depth interviews were conducted with ten purposively chosen respondents which comprised of former and serving lawmakers, party chairman, local government chairman, a labour leader, member of a social cultural group, and a serving commissioner. The secondary data was sourced from journal articles, books, newspapers and online publications. The primary and secondary data were content analyzed. The study found that political elites used the electorate to achieve their selfish political agenda; politics of exclusion is responsible for the poor participation of the people in partisan politics, undermining of democratic principles, and breeding of political violence in Oyo state, Nigeria. The study recommended that the Nigerian youths need to be more assertive to demand for accountability from political actors; while political elites should learn to do away with selfish interests. In addition, rule of law, freedom of the press and independence of the judiciary must be upheld in the country.