Chemical Studies and Antibacterial Activity of the Root of Rumex abyssinicus
Open Access
- 28 July 2020
- journal article
- Published by Earthline Publishers in Earthline Journal of Chemical Sciences
- Vol. 4 (2), 155-173
- https://doi.org/10.34198/ejcs.4220.155173
Abstract
One of the Ethiopian endemic plants used traditionally as medicine for different diseases is Rumex abyssinicus. It is widely known as ‘Meqmeqo’ in Amharic. The aim of this study was to isolate and characterize compounds from the root of R. abyssinicus and to test their bioactivities of solvent fractions of the extract. The crude extract was extracted from dried powdered root of the plant with methanol. Then it was fractionated with n‑hexane and ethyl acetate with increasing polarity. The yellow powder obtained from ethyl acetate fractionation was applied to column chromatographic separation that led to the isolation of two compounds, diisobutyl phthalate and emodine. Finally, antibacterial evaluation of the ethyl acetate and methanol soluble portions were carried out against four pathogenic bacteria. Both methanol and ethyl acetate soluble portions inhibited all selected bacterial in better at high concentrations.Keywords
This publication has 15 references indexed in Scilit:
- Antibacterial and antagonistic activity of selected traditional medicinal plants and herbs from East Wollega Zone against clinical isolated human pathogensScience, Technology and Arts Research Journal, 2016
- An Overview of Ethiopian Traditional Medicinal Plants Used for Cancer TreatmentEuropean Journal of Medicinal Plants, 2016
- Evaluation of wound healing and anti-inflammatory activity of the rhizomes of Rumex abyssinicus J. (Polygonaceae) in miceBMC Complementary and Alternative Medicine, 2015
- Antimicrobial activities of six plants used in Traditional Arabic Palestinian Herbal MedicineAfrican Journal of Microbiology Research, 2014
- Medicinal plants used in traditional medicine by Oromo people, Ghimbi District, Southwest EthiopiaJournal of Ethnobiology and Ethnomedicine, 2014
- Phytochemical analysis of the methanol leaves extract of Paullinia pinnata linnJournal of Pharmacognosy and Phytotherapy, 2014
- Evaluation of the In Vitro Efficacy of Artemisia annua, Rumex abyssinicus, and Catha edulis Forsk Extracts in Cancer and Trypanosoma brucei CellsISRN Biochemistry, 2013
- Evaluation of the phytochemical and hemostatic potential of Jatropha multifida sapAfrican Journal of Pharmacy and Pharmacology, 2012
- Plant use in Odo-Bulu and Demaro, Bale region, EthiopiaJournal of Ethnobiology and Ethnomedicine, 2011
- Knowledge and use of medicinal plants by people around Debre Libanos monastery in EthiopiaJournal of Ethnopharmacology, 2007