Pathophysiology and Prevention of Paracentesis-induced Circulatory Dysfunction: A Concise Review
Open Access
- 26 March 2020
- journal article
- review article
- Published by Xia & He Publishing in Journal of Clinical and Translational Hepatology
- Vol. 8 (X), 1-7
- https://doi.org/10.14218/jcth.2019.00048
Abstract
Annually, 10% of cirrhotic patients with ascites develop refractory ascites for which large-volume paracentesis (LVP) is a frequently used therapeutic procedure. LVP, although a safe method, is associated with circulatory dysfunction in a significant percentage of patients, which is termed paracentesis-induced circulatory dysfunction (PICD). PICD results in faster reaccumulation of ascites, hyponatremia, renal impairment, and shorter survival. PICD is diagnosed through laboratory results, with increases of >50% of baseline plasma renin activity to a value ≥4 ng/mL/h on the fifth to sixth day after paracentesis. In this review, we discuss the pathophysiology and prevention of PICD.Keywords
This publication has 52 references indexed in Scilit:
- Albumin Reduces Paracentesis-Induced Circulatory Dysfunction and Reduces Death and Renal Impairment among Patients with Cirrhosis and Infection: A Systematic Review and Meta-AnalysisBioMed Research International, 2013
- Continuous terlipressin versus vasopressin infusion in septic shock (TERLIVAP): a randomized, controlled pilot studyCritical Care, 2009
- Comparison of outcome in patients with cirrhosis and ascites following treatment with albumin or a synthetic colloid:Liver International, 2005
- Renal and neurohormonal changes following simultaneous administration of systemic vasoconstrictors and dopamine or prostacyclin in cirrhotic patients with hepatorenal syndromeJournal of Hepatology, 1996
- Efficacy and safety of the stepped care medical treatment of ascites in liver cirrhosis: a randomized controlled clinical trial comparing two diets with different sodium contentLiver International, 1993
- Age-Related Changes in the Renin-Aldosterone SystemDrugs & Aging, 1993
- Effects of therapeutic paracentesis on systemic and hepatic hemodynamics and on renal and hormonal functionJournal of Hepatology, 1987
- Changes in plasma renin activity in cirrhosis: a reappraisal based on studies in 67 patients and "low-renin" cirrhosis.Hypertension, 1979
- Postural Augmentation of Plasma Renin Activity and Aldosterone Excretion in Normal People*JCI Insight, 1967
- Noradrenaline, Adrenaline, and the Human CirculationBMJ, 1952