Crystal structure of methyl 1-methyl-3,5-diphenyl-7-tosyl-3,6,7,11b-tetrahydropyrazolo[4′,3′:5,6]pyrano[3,4-c]quinoline-5a(5H)-carboxylate

Abstract

In the title compound, C35H31N3O5S, the piperidine ring adopts an envelope conformation, with the methine C atom as the flap, and the pyran ring adopts a sofa conformation. The mean planes of these two rings are almost normal to one another, making a dihedral angle of 85.96 (5)degrees. The two phenyl rings, one attached to the pyrazole ring and the other to the pyran ring, are inclined to one another by 65.41 (11)degrees. They are inclined to the mean planes of the rings to which they are attached by 12.59 (11) and 70.09 (9)degrees, respectively. There is an intramolecular C-H center dot center dot center dot pi interaction involving the tosylate methyl group and the phenyl ring attached to the pyrazole ring. In the crystal, molecules are linked by C-H center dot center dot center dot pi interactions, forming ribbons parallel to (102). The ribbons are linked by slipped parallel pi-pi interactions involving inversion-related pyrazole rings [inter-centroid distance = 3.672 (2) angstrom], forming slabs parallel to (001). A preliminary report of this structure has been published [Bakthadoss et al. (2014). Eur. J. Org. Chem. pp. 1505-1513].