Correlation between Bacterial Vaginosis, HPV Infection and Cervical Lesions

Abstract

Bacterial vaginosis (BV) is the most common lower genital tract infection among women of childbearing age. It is most common among women infected with human papillomavirus. However, the correlation between BV, HPV and the development of cervical lesions is still unclear. In recent years, studies have found that BV can cause cervical intraepithelial neoplasia and cervical cancer by destroying the immune regulation mechanism of the body. Although the traditional antibiotic treatment of BV is effective, the cure rate is low and the recurrence rate is high. At present, probiotics have become a new therapy by reshaping the female vaginal micro-ecological environment. Therefore, it is possible to prevent cervical intraepithelial neoplasia and cervical cancer by improving the immune response to HPV infection by improving the vaginal micro-ecological imbalance.