Sirt1 activator SRT2104 protects against oxygen-glucose deprivation/reoxygenation-induced injury via regulating microglia polarization by modulating Sirt1/NF-κB pathway
- 4 January 2021
- journal article
- research article
- Published by Elsevier BV in Brain Research
- Vol. 1753, 147236
- https://doi.org/10.1016/j.brainres.2020.147236
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- Pharmacokinetics and tolerability of SRT2104, a first‐in‐class small molecule activator of SIRT1, after single and repeated oral administration in manBritish Journal of Clinical Pharmacology, 2012
- Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral IschemiaStroke, 2012
- Stroke Epidemiology: Advancing Our Understanding of Disease Mechanism and TherapyNeurotherapeutics, 2011
- Mammalian Sirt1: insights on its biological functionsCell Communication and Signaling, 2011
- SIRT1: recent lessons from mouse modelsNature Reviews Cancer, 2010
- Inflammatory mechanisms in ischemic stroke: role of inflammatory cellsJournal of Leukocyte Biology, 2010
- Caloric restriction, SIRT1 and longevityTrends in Endocrinology & Metabolism, 2009
- Debris clearance by microglia: an essential link between degeneration and regenerationBrain, 2008
- SIRT1 promotes DNA repair activity and deacetylation of Ku70Experimental & Molecular Medicine, 2007
- Effects of Thiazolidinediones on Stroke Recovery: A Case-Matched Controlled StudyNeurochemical Research, 2006