Acoustic radiation force impulse elastography findings of achilles tendon in patients with hypothyroidism
Open Access
- 29 July 2021
- journal article
- Published by Turkish Journal of Internal Medicine in Turkish Journal of Internal Medicine
- Vol. 3 (3), 102-108
- https://doi.org/10.46310/tjim.869648
Abstract
Introduction The aim of our study was to investigate the effect of thyroid dysfunction on tendons and the contribution of Acoustic Radiation Force Impulse (ARFI) elastography to the diagnosis of tendinopathy. Methods Eighty Achilles tendons of 40 patients under levothyroxine treatment, who had previously known hypothyroidism but high serum thyroid stimulating hormone levels, and 80 Achilles tendons of 40 healthy individuals were evaluated with ARFI (Virtual Touch Quantification®). 19 of 40 of the patients with hypotiroidism’ Achilles tendons were re-evaluated after thyroid stimulating hormone levels reached to normal limits following the adjustments in thyroid hormone replacement therapy. The middle portion of the each Achilles tendon was chosen for the examination. Every examination consisted of three to five independent measurements (shear wave velocity- meters per second). The mean shear wave velocity value was calculated for each tendon, and used for statistical analysis. Results The stiffness values of both left and right Achilles tendons, represented as shear wave velocity, were similar in patients with hypothyroidism and control group. There was no significant difference between the Achilles tendon shear wave velocity measurements of 19 of 40 hypothyroidism patients who were re-evaluated after the adjustments in thyroid hormone replacement therapy. Conclusions The lack of significant difference in Achilles tendon stiffness between non-naive hypothyroid patients and the control group may be explained as a positive clinical effect of thyroid hormone replacement therapy.Keywords
Funding Information
- Baskent Üniversitesi (KA19/44)
This publication has 25 references indexed in Scilit:
- Thyroid hormones enhance growth and counteract apoptosis in human tenocytes isolated from rotator cuff tendonsCell Death & Disease, 2013
- Real-time sonoelastography of Achilles tendon in patients with ankylosing spondylitisSkeletal Radiology, 2013
- Real-Time Sonoelastography: Findings in Patients with Symptomatic Achilles Tendons and Comparison to Healthy VolunteersUltraschall in der Medizin - European Journal of Ultrasound, 2009
- Phenotypic responses to mechanical stress in fibroblasts from tendon, cornea and skinBiochemical Journal, 2006
- Are ultrasound and magnetic resonance imaging of value in assessment of Achilles tendon disorders? A two year prospective studyBritish Journal of Sports Medicine, 2003
- Ultrasonography in the Differential Diagnosis of Achilles Tendon Injuries and Related DisordersActa Radiologica, 1998
- Hypothyroidism Presenting as TendinitisThe Physician and Sportsmedicine, 1997
- Rheumatic symptoms associated with hypothyroidism in childrenThe Journal of Pediatrics, 1993
- Unusual manifestations of hypothyroidismArchives of Internal Medicine, 1984
- Joint effusions, chondrocalcinosis and other rheumatic manifestations in hypothyroidismThe American Journal of Medicine, 1975