Telomerase Dysfunction in the Tumorigenesis of Genetic Disorders
Open Access
- 1 December 2021
- journal article
- research article
- Vol. 10 (1), 56-67
- https://doi.org/10.22088/IJMCM.BUMS.10.1.56
Abstract
Telomeres are nucleoprotein complexes present at the ends of chromosome to maintain its integrity. Telomere length is maintained by an enzyme called "telomerase". Thus, telomerase activity and telomere length are crucial for the initiation of cancer and tumors survival. Also, oxidative stress will cause DNA, protein, and/or lipid damage, which ...Keywords
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