An Insight into Different Strategies for Control and Prophylaxis of Fasciolosis: A Review

Abstract
Fasciolosis is one of the important diseases of livestock and has zoonotic importance. Fasciolosis can cause huge economic losses due to decrease in milk and meat production, decreased feed conversion ratio, and cost of treatment. Treatment and prophylaxis strategies for Fasciola infection are formed based on epidemiological data. The control of Fasciola infection can be attained by treating the animals with active anthelmintics. The use of different combinations of anthelmintics with a possible rotation is more effective against immature as well as adult flukes. Control of the intermediate host (snail) is vital for the reduction of fasciolosis. Due to the rapid growth of snails, the eradication is quite difficult in waterlogged and marshy areas. The use of different grazing methods and treatment of grazing areas can also help to control fasciolosis. A variety of antigens generated by Fasciola spp. have been shown to protect against liver fluke infection. The crude antigens, excretory/secretory, and refined antigens and their combination can be used as prophylactic treatment for the control of fasciolosis. The use of any of the single or combination of these methods can be very effective for the control of fasciolosis.