Rapid hemostasis and high bioactivity cerium‐containing mesoporous bioglass for hemostatic materials
- 15 December 2021
- journal article
- research article
- Published by Wiley in Journal of Biomedical Materials Research Part B: Applied Biomaterials
- Vol. 110 (6), 1255-1264
- https://doi.org/10.1002/jbm.b.34996
Abstract
A two-step-acid-catalyzed-self-assembly method was used to prepare cerium-containing mesoporous bioactive glass with P123 as a template. The results showed that MBG without cerium and MBG with cerium slightly affected its surface area, and its water absorption rate was significantly higher. In vitro coagulation experiments showed that Ce-MBG significantly reduces prothrombin time (PT) and activated partial thromboplastin time (APTT), indicating that MBG containing Ce could promote coagulation and platelet adhesion compared with MBG. These suggested that Ce-MBG may be a good dressing with hemostatic properties, which could shorten the bleeding time of the wound and control the bleeding.Keywords
This publication has 38 references indexed in Scilit:
- Curcumin release from cerium, gallium and zinc containing mesoporous bioactive glassesMicroporous and Mesoporous Materials, 2013
- Substitutions of cerium, gallium and zinc in ordered mesoporous bioactive glassesActa Biomaterialia, 2011
- Interaction of Mesoporous Silica Nanoparticles with Human Red Blood Cell Membranes: Size and Surface EffectsACS Nano, 2011
- Effect of cerium ion on the proliferation, differentiation and mineralization function of primary mouse osteoblasts in vitroJournal of Rare Earths, 2010
- Formation of porous PLGA scaffolds by a combining method of thermally induced phase separation and porogen leachingJournal of Applied Polymer Science, 2008
- Platelet adsorption and hemolytic properties of liquid crystal/composite polymersInternational Journal of Pharmaceutics, 2006
- The in-vitro bioactivity of mesoporous bioactive glassesBiomaterials, 2006
- Oxide Hemostatic ActivityJournal of the American Chemical Society, 2006
- Cerium and yttrium oxide nanoparticles are neuroprotectiveBiochemical and Biophysical Research Communications, 2006
- Well-ordered mesoporous bioactive glasses (MBG): A promising bioactive drug delivery systemJournal of Controlled Release, 2006