The Use of Hydrogel Dressings in Sulfur Mustard-Induced Skin and Ocular Wound Management
Open Access
- 2 June 2023
- journal article
- review article
- Published by MDPI AG in Biomedicines
- Vol. 11 (6), 1626
- https://doi.org/10.3390/biomedicines11061626
Abstract
Over one century after its first military use on the battlefield, sulfur mustard (SM) remains a threatening agent. Due to the absence of an antidote and specific treatment, the management of SM-induced lesions, particularly on the skin and eyes, still represents a challenge. Current therapeutic management is mainly limited to symptomatic and supportive care, pain relief, and prevention of infectious complications. New strategies are needed to accelerate healing and optimize the repair of the function and appearance of damaged tissues. Hydrogels have been shown to be suitable for healing severe burn wounds. Because the same gravity of lesions is observed in SM victims, hydrogels could be relevant dressings to improve wound healing of SM-induced skin and ocular injuries. In this article, we review how hydrogel dressings may be beneficial for improving the wound healing of SM-induced injuries, with special emphasis placed on their suitability as drug delivery devices on SM-induced skin and ocular lesions.Funding Information
- French Ministry of Armed Forces (Biomedef NBC-5-C-2204)
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