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Refractory Arterial Hypotension in a Patient with COVID-19: Could the Hypothalamic-Pituitary-Adrenal Axis Be Involved? Case Report and Mini Review

Francisco E. Finamor, Luciana P. Finamor, Frederico J. N. Mancuso, Jaquelina S. Ota-Arakaki, Marcelo R. S. Moraes, Cristina Muccioli, Nancy Bellei
Advances in Infectious Diseases , Volume 10, pp 160-167; doi:10.4236/aid.2020.103016

Abstract: Neuro-endocrinological manifestations rarely are described in cases of SARS- CoV-2. We describe a case of a previously hypertensive patient who presented COVID-19 and developed refractory arterial hypotension. In the investigation, low levels of ACTH and cortisol were observed, suggesting secondary adrenal insufficiency as the cause of refractory hypotension.
Keywords: Adrenal insufficiency / ACTH / Arterial Hypotension / Hypocortisolism / COVID-19

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