Differential Effect of Growth on Development between AGA and SGA Preterm Infants
Open Access
- 27 April 2020
- journal article
- research article
- Published by MDPI AG in International Journal of Environmental Research and Public Health
- Vol. 17 (9), 3022
- https://doi.org/10.3390/ijerph17093022
Abstract
Predicting developmental outcomes with growth measurement would be beneficial for primary healthcare or in developing countries with low medical resources. This study aimed to identify physical growth measures that indicate neurodevelopment in very preterm infants. Preterm infants, born at <32 weeks’ gestation or weighing <1500 g, were included. We calculated the changes in z-score of weight, length, and head circumference (HC) at different time points: birth, postmenstrual age (PMA) 35 weeks, and 4 and 18 months corrected age (CA). We examined the relationship between growth and Bayley-III scores using linear regression. Among 122 infants, HC at 4 months CA and HC growth between PMA 35 weeks and 4 months CA showed a positive correlation with Bayley-III scores in appropriate-for-gestational-age infants (AGAs). Weight and length increases between birth and 18 months CA were also associated with AGAs’ development. In small-for-gestational-age infants (SGAs), only birthweight’s z-score was associated with improved neurodevelopmental outcomes. HC at 4 months CA was an important indicator of favorable neurodevelopmental outcomes, and head growth spurt between PMA 35 weeks and 4 months CA contributed to this benefit in preterm AGAs. The period and indices should be monitored differently for SGAs and AGAs.This publication has 22 references indexed in Scilit:
- The Relationship of Poor Linear Growth Velocity with Neonatal Illness and Two-Year Neurodevelopment in Preterm InfantsNeonatology, 2012
- Infant Growth Before and After Term: Effects on Neurodevelopment in Preterm InfantsPEDIATRICS, 2011
- Body Composition Changes in Preterm Infants Following Hospital DischargeJournal of Pediatric Gastroenterology and Nutrition, 2011
- Postnatal growth of preterm born children ≤750g at birthEarly Human Development, 2011
- Head circumference catch-up growth among preterm very low birth weight infants: effect on neurodevelopmental outcomejpme, 2011
- First year growth among very low birth weight infantsActa Paediatrica, 2010
- Intrauterine, Early Neonatal, and Postdischarge Growth and Neurodevelopmental Outcome at 5.4 Years in Extremely Preterm Infants After Intensive Neonatal Nutritional SupportPEDIATRICS, 2009
- Extrauterine growth restriction in very‐low‐birthweight infantsActa Paediatrica, 2004
- Developmental science and the media: Early brain development.American Psychologist, 2001
- Developmental science and the media: Early brain development.American Psychologist, 2001