Simultaneous Presence of Acetylcholine Receptor and Muscle Specific Tyrosine Kinase Antibodies in Myasthenia Gravis
Open Access
- 31 December 2019
- journal article
- Published by Maad Rayan Publishing Company in International Journal of Basic Science in Medicine
- Vol. 4 (4), 128-130
- https://doi.org/10.34172/ijbsm.2019.01
Abstract
Myasthenia gravis (MG) is known as an autoimmune disorder which affects transmission in neuromuscular junction. The serologic tests used for diagnosis include acetylcholine receptor and muscle specific receptor tyrosine kinase antibodies. Studies often have reported that patients with formal antibody are negative for the latter one. However, very limited studies have reported positive anti-muscle specific receptor tyrosine kinase antibody in a small percentage of patients with acetylcholine receptor antibody. Here, we reported a young woman who was diagnosed with MG and had a rapid and progressive course of the disease. She was seropositive for both acetylcholine receptor and muscle-specific receptor tyrosine kinase antibodies simultaneously. However, she discharged from the hospital with good condition after treatment.Keywords
This publication has 12 references indexed in Scilit:
- Coexistence of autoimmune diseases and autoantibodies in patients with myasthenia gravisNeurology India, 2016
- Myasthenia Gravis Presenting Initially as Acute Respiratory FailureRespiratory Care, 2014
- Treatment of MuSK-Associated Myasthenia GravisCurrent Treatment Options in Neurology, 2014
- Do acetylcholine receptor and striated muscle antibodies predict the presence of thymoma in patients with myasthenia gravis?Muscle & Nerve, 2013
- Update on muscle-specific tyrosine kinase antibody positive myasthenia gravisCurrent Opinion in Neurology, 2010
- Clinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravisNeurology, 2007
- Patterns and severity of neuromuscular transmission failure in seronegative myasthenia gravisJournal of Neurology, Neurosurgery & Psychiatry, 2005
- Detection and characterization of MuSK antibodies in seronegative myasthenia gravisAnnals of Neurology, 2004
- Seronegative Myasthenia GravisSeminars in Neurology, 2004
- Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravisBrain, 2003