Contribution of smFRET to Chromatin Research
Open Access
- 8 February 2023
- journal article
- review article
- Published by MDPI AG in Biophysica
- Vol. 3 (1), 93-108
- https://doi.org/10.3390/biophysica3010007
Abstract
Chromatins are structural components of chromosomes and consist of DNA and histone proteins. The structure, dynamics, and function of chromatins are important in regulating genetic processes. Several different experimental and theoretical tools have been employed to understand chromatins better. In this review, we will focus on the literatures engrossed in understanding of chromatins using single-molecule Förster resonance energy transfer (smFRET). smFRET is a single-molecule fluorescence microscopic technique that can furnish information regarding the distance between two points in space. This has been utilized to efficiently unveil the structural details of chromatins.Keywords
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