Simultaneous electrochemical determination of epinephrine and acetylcholine using modified screen printed electrode
Open Access
- 1 May 2020
- journal article
- research article
- Published by Sami Publishing Company in Eurasian Chemical Communications
- Vol. 2 (5), 563-572
- https://doi.org/10.33945/sami/ecc.2020.5.1
Abstract
Electrochemical behaviors of epinephrine and acetylcholine were investigated, using cyclic voltammetry, on the Ag-ZnO modified screen-printed electrode (Ag-ZnO/SPE). Ag-ZnO nanoplates showed excellent electrocatalytic activity toward the oxidation of epinephrine and acetylcholine compared with bare SPE in 0.1 M PBS. Under the optimized experimental conditions, a linear response obtained in the range of 0.13 to 450.00 μM with detection limit of 0.04 μM for epinephrine. Ag-ZnO/SPE exhibits good stability, reproducibility and repeatability, and the method has been successfully applied for detection of epinephrine and acetylcholine in their pharmaceutical and biological samples with satisfactory recovery.Keywords
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