Preparation and characterization of surface active N-butyrated low molecular weight chitosan
Open Access
- 31 March 2016
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 7 (1), 91-96
- https://doi.org/10.5155/eurjchem.7.1.91-96.1353
Abstract
New classes of natural surfactants have been prepared through the reaction of low molecular weight chitosans (1.3, 6, 10, 18 and 30 kDa) with butyric anhydride in aqueous medium. The new compounds were characterized by 1H NMR and FT-IR spectroscopy. Their surface tension and particle size were also determined. The degree of substitutions was in the range of 44-57% as confirmed by 1H NMR spectra. These compounds possess low aggregate size 12-18 nm with higher surface activity on comparison with native chitosan. The prepared compounds are found to be soluble in all pH media in contrast to native chitosan. This may be due to the breaking up of chitosans inter-strand hydrogen bonding upon substitutes.Keywords
This publication has 24 references indexed in Scilit:
- Characterization of drug–chitosan interaction by 1H NMR, FTIR and isothermal titration calorimetryEuropean Journal of Pharmaceutics and Biopharmaceutics, 2008
- Preparation of polymeric micelles based on chitosan bearing a small amount of highly hydrophobic groupsCarbohydrate Polymers, 2006
- Chitin and chitosan: Properties and applicationsProgress in Polymer Science, 2006
- Heterogeneous catalysis on chitosan-based materials: a reviewProgress in Polymer Science, 2005
- Recent developments in polysaccharide-based materials used as adsorbents in wastewater treatmentProgress in Polymer Science, 2005
- Preparation and physico-chemical characterization of chitin and chitosan from the pens of the squid species, Loligo lessoniana and Loligo formosanaCarbohydrate Polymers, 2004
- A validated 1H NMR method for the determination of the degree of deacetylation of chitosanJournal of Pharmaceutical and Biomedical Analysis, 2003
- Ionic conductivity of chitosan membranesPolymer, 2003
- Formulation pH modulates the interaction of insulin with chitosan nanoparticlesJournal of Pharmaceutical Sciences, 2002
- Novel injectable neutral solutions of chitosan form biodegradable gels in situBiomaterials, 2000