The Panacea of Human Aging: Calorie Restriction Versus Exercise
- 17 April 2019
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Exercise and Sport Sciences Reviews
- Vol. 47 (3), 169-175
- https://doi.org/10.1249/jes.0000000000000193
Abstract
Primary aging is the progressive decline in health and fitness and depends on metabolic rate and oxidative stress. Untoward changes in body composition and metabolic function characterize secondary aging. We hypothesize that both exercise and calorie restriction (CR) improve secondary aging, but only CR improves primary. However, CR followed with exercise is a superior strategy to maintain overall health and quality of life with age.Keywords
This publication has 50 references indexed in Scilit:
- Effect of 6-Month Calorie Restriction on Biomarkers of Longevity, Metabolic Adaptation, and Oxidative Stress in Overweight IndividualsJAMA, 2006
- Long-Term Caloric Restriction Ameliorates the Decline in Diastolic Function in HumansJournal of Invasive Cardiology, 2006
- Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humansProceedings of the National Academy of Sciences of the United States of America, 2004
- Calorie restriction and aging: review of the literature and implications for studies in humansThe American Journal of Clinical Nutrition, 2003
- Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock FactorScience, 2003
- Effects of the Amount and Intensity of Exercise on Plasma LipoproteinsThe New England Journal of Medicine, 2002
- Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot‐2 (mortalin)/mthsp70/Grp75FEBS Letters, 2002
- Reduction in Obesity and Related Comorbid Conditions after Diet-Induced Weight Loss or Exercise-Induced Weight Loss in MenAnnals of Internal Medicine, 2000
- The biology of aging.2000
- Aging: A Theory Based on Free Radical and Radiation ChemistryJournal of Gerontology, 1956