Loss of a Branch Sugar in the Acinetobacter baumannii K3-Type Capsular Polysaccharide Due To Frameshifts in the <i>gtr6</i> Glycosyltransferase Gene Leads To Susceptibility To Phage APK37.1

doi:10.1128/spectrum.03631-22

Loss of a Branch Sugar in the Acinetobacter baumannii K3-Type Capsular Polysaccharide Due To Frameshifts in the gtr6 Glycosyltransferase Gene Leads To Susceptibility To Phage APK37.1

Olga Y. Timoshina, Anastasiya A. Kasimova, Mikhail M. Shneider, Nikolay P. Arbatsky, Alexander S. Shashkov, Andrey A. Shelenkov, Yuliya V. Mikhailova,

Anastasiya V. Popova

Ruth M. Hall

, Yuriy A. Knirel,

Published: 18 January 2023

by American Society for Microbiology

in Microbiology Spectrum

Microbiology Spectrum ; https://doi.org/10.1128/spectrum.03631-22

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Abstract: Lytic bacteriophage have potential for the treatment of otherwise untreatable extensively antibiotic-resistant bacteria. For Acinetobacter baumannii , most phage exhibit specificity for the type of capsular polysaccharide (CPS) produced on the cell surface.

Keywords: treatment / Acinetobacter / baumannii / type of capsular polysaccharide / Branch / Loss

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Loss of a Branch Sugar in the Acinetobacter baumannii K3-Type Capsular Polysaccharide Due To Frameshifts in the gtr6 Glycosyltransferase Gene Leads To Susceptibility To Phage APK37.1

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