Breast cancer screening program in Lithuania: trends in breast cancer mortality before and during the introduction of the mammography screening programme
Open Access
- 23 December 2020
- journal article
- Published by Vilnius University Press in Acta medica Lituanica
- Vol. 27 (2), 60-68
- https://doi.org/10.15388/amed.2020.27.2.3
Abstract
BackgroundBreast cancer is the most frequent oncological disease as well as the leading cause of cancer death among women worldwide. Decline in mortality in economically strong countries is observed. This decline is mostly related to early diagnosis (improvement in breast cancer awareness and mammography screening program (MSP)) and more effective treatment. In the end of 2005, the MSP started in Lithuania. The main aim of this article was to evaluate breast cancer mortality during 22 years in Lithuania, as well as changes before the start of the MSP and during its implementation, in order to assess the influence of the MSP on mortality. Materials and MethodsAnalysis was based on data from the population-based Lithuanian Cancer Registry. Analysis of changes in mortality included the period from 1998 to 2019. Age standardized mortality rates were calculated for assessment of changes. Join-point regression analysis was used. ResultsApplying the segmental regression model, it was found that during the study period mortality was statistically significantly decreasing by -1.1% each year. Mortality among women under the age of 50 decreased both before and during the implementation of MSP. Mortality in the target population also was already decreasing until the implementation of the program, but since 2006 significant reduction in mortality was observed in this group. ConclusionsOverall breast cancer mortality is decreasing in Lithuania. After the implementation of MSP the largest reduction in mortality was observed among the target population, however, it is not as pronounced as it could be with the well-organized MSP.Keywords
This publication has 25 references indexed in Scilit:
- The benefits and harms of breast cancer screening: an independent reviewBritish Journal of Cancer, 2013
- Screening for breast cancer with mammographyEmergencias, 2013
- Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012European Journal of Cancer, 2013
- The benefits and harms of breast cancer screening: an independent reviewThe Lancet, 2012
- Mammography activity in Norway 1983 to 2008Acta Oncologica, 2011
- Disparities in breast cancer mortality trends between 30 European countries: retrospective trend analysis of WHO mortality databaseBMJ, 2010
- Breast cancer mortality in Barcelona following implementation of a city breast cancer-screening programCancer Detection Prevention, 2008
- Effect of Screening and Adjuvant Therapy on Mortality from Breast CancerThe New England Journal of Medicine, 2005
- Initiation of population-based mammography screening in Dutch municipalities and effect on breast-cancer mortality: a systematic reviewThe Lancet, 2003
- UK and USA breast cancer deaths down 25% in year 2000 at ages 20–69 yearsThe Lancet, 2000