Drug adherence among adult hypertensives attending medical out-patient clinic in a tertiary hospital in Ogun State, Nigeria

Abstract

Objective: The research aimed to estimate the level of drug adherence, to determine the reasons for non-adherence, and identify risk factors associated with non -adherence among adult hypertensive clients attending an out-patient clinic in Ogun State, Nigeria. Methodology: A descriptive cross-sectional study of adults with hypertension at a medical outpatient clinic in a tertiary hospital. Four hundred and four (404) respondents were selected from November 2015 to April 2016, a validated questionnaire by Morisky Green was adapted and distributed by trained research assistants. The chi-square test was used to compare categorical variables like sex, marital status, and clinic attendance among the two groups of adherent and non-adherent hypertensive. Information was summarized using frequency tables and cross-tabulations. Binary logistic regression analysis was done. The level of significance was set at 5%. Results: Optimal adherence was observed in 281(69.0%) of the respondents. Being a female (OR: 1.833; 1.048 -7.205, p=0.034), being employed (OR: 2.099; 1.097-4.096, p=0.03) and regular clinic attendance (OR: 22.26; 12.647 – 39.107, p