A COMPARATIVE STUDY OF DIAGNOSTIC ACCURACY OF A POINT-OF-CARE SCREENING TEST VIS-À-VIS A GOLD STANDARD TEST FOR DIAGNOSIS OF COVID-19 IN CASES OF SURGICAL EMERGENCIES
- 1 January 2022
- journal article
- Published by World Wide Journals
Abstract
In this COVID – 19 pandemic, there's an urgent need for a sensitive and specic test which provides results in a short span of time. Rapid Antigen Tests, have the potential to replace RT-PCR tests as a conrmatory test. A comparative study of Point-of-Care test vis-à-vis gold standard test was carried out by the Surgical Department of a secondary level care hospital. A total of 112 patients, with various surgical emergencies were tested, by RADT and by RT-PCR for conrmation. Patients were managed based on RADT results as per the institutional algorithm. 107 RADTs tested negative while ve tested positive. 105 RT-PCR tested negative while seven tested positive. Two patients reported negative by RADT were reported as RT-PCR positive. Although RADTs have the potential, their sensitivity is highly variable. To establish them as diagnostic tests of choice, RADTs need to be developed further so as to ensure that their sensitivity is high and results are reproducible across multiple centers.Keywords
This publication has 11 references indexed in Scilit:
- Mask-wearing and control of SARS-CoV-2 transmission in the USA: a cross-sectional studyThe Lancet Digital Health, 2021
- Diagnosis of COVID-19 for controlling the pandemic: A review of the state-of-the-artBiosensors and Bioelectronics, 2020
- COVID-19 diagnosis —A review of current methodsBiosensors and Bioelectronics, 2020
- Evaluation of a Rapid Diagnostic Assay for Detection of SARS-CoV-2 Antigen in Nasopharyngeal SwabsJournal of Clinical Microbiology, 2020
- The airborne lifetime of small speech droplets and their potential importance in SARS-CoV-2 transmissionProceedings of the National Academy of Sciences of the United States of America, 2020
- Development and Potential Usefulness of the COVID-19 Ag Respi-Strip Diagnostic Assay in a Pandemic ContextFrontiers in Medicine, 2020
- Genomic characterization of a novel SARS-CoV-2Gene Reports, 2020
- A Novel Coronavirus from Patients with Pneumonia in China, 2019The New England Journal of Medicine, 2020
- Definition of Emergency General Surgery (EGS) and Its Burden on the SocietyPublished by Springer Science and Business Media LLC ,2018
- Johnstone, Maj.-Gen. Robert Maxwell, (9 March 1914–11 March 1990), Assistant Director (Overseas), British Postgraduate Medical Federation, 1970–76Published by Oxford University Press (OUP) ,2007