Despite the importance of promoting entrepreneurship in business activities to achieve a competitive advantage, a large proportion of business firms fail to make entrepreneurship a reality in their work. In addition, these constraints make it possible to gain a competitive advantage in the problems of the market in particular that modern markets are full of rivals and fast-paced changes in various variables. In light of this, the researcher carried out this study to investigate the role of entrepreneurship in achieving competitive advantage in SMEs. By using the descriptive-analytical approach, developing a questionnaire tool and distributing it to a sample of 100 administrators working in SMEs in Saudi Arabia. The results of the study showed that there is a positive relationship in the role of entrepreneurship in achieving competitive advantage in small and medium enterprises in the Kingdom of Saudi Arabia.