78 years old gentleman diagnosed as non-ST-segment elevation acute coronary syndrome (NSTE-ACS). The Culprit lesion was a mid left anterior descending artery (LAD) stenosis (arrow A), a similar lesion to the first in-man coronary angioplasty which was performed at the same cardiac center (University Heart Center Zurich) (arrow B) exactly the same day (arrow C) 40 years back (16th September 1977) by Dr. Andreas R. Grüntzig! This time the lesion was treated with drug-eluting stent (arrow E) that considered a gold standard now.