Abstract
The 30th annual Transcatheter Cardiovascular Therapeutics (TCT) conference 2018 held in sunny San Diego, California, was replete with surprises. The landmark COAPT trial was a clear home run, showcasing that transcatheter mitral valve approximation using the MitraClip, on a background of maximally tolerated guideline-directed medical therapy (GDMT) was superior to GDMT alone in the reduction of Heart Failure (HF) hospitalization and mortality in symptomatic heart failure patients with grade 3-4+ Mitral regurgitation (MR).