Serum Neurostatin Level in Patients with Heart Failure and Its Relationship with the Severity of Heart Failure

Abstract

目的：观察心力衰竭患者血清中neuronostatin水平及其与心衰严重程度的关系，探讨其临床意义。方法：选择其中射血分数降低的62例心衰患者作为实验组，并选取同期非心衰患者72例为对照组，采用酶联免疫吸附试验(ELISA)测定血清中neuronostatin水平。结果：心衰组血清中neuronostatin的水平较非心衰组明显升高，差异有统计学意义(p Objective: To observe the serum neuronostatin level in patients with heart failure and its relationship with the severity of heart failure, and to explore its clinical significance. Methods: 62 patients with heart failure with reduced ejection fraction were selected as the experimental group, and 72 patients with non-heart failure during the same period were selected as the control group. The level of neuronostatin in serum was determined by enzyme-linked immunosorbent assay (ELISA). Results: The level of neuronostatin in the serum of the heart failure group was significantly higher than that of the non-heart failure group, and the difference was statistically significant (p