Cough is a sudden and often repetitively occurring reflex which helps to clear the large breathing passages. It is a protective reflex against foreign material. It is the most common presenting complaint in outpatient department. Cough may represent a symptom of simple common cold as well as of fatal Lung carcinoma. The curative effects of lesser known homoeopathic medicines in the cases of cough have been explored by proving and clinical verification. The role of these medicines should be further explored and identified, especially in clinical practice, to strengthen the Materia medica. This article reviews the therapeutic indications of lesser known homoeopathic drugs in the management of cough.