Association between the prognostic nutritional index and severe headache or migraine: a population-based study
- 17 November 2022
- journal article
- research article
- Published by Taylor & Francis Ltd in Nutritional Neuroscience
- Vol. 26 (12), 1202-1211
- https://doi.org/10.1080/1028415x.2022.2143958
Abstract
Migraine is a highly prevalent headache disorder, and intake of various nutrients and special diets may improve migraine symptoms. We aimed to clarify the association between nutritional status and migraine. We collected the data of 1838/8953 (migraineurs/all participants) from the National Health and Nutrition Examination Survey (NHANES) 1999–2004 cycle. We used weighted multivariable linear or logistic regression analyses to study the association between the prognostic nutritional index (PNI) and the occurrence of severe headache or migraine. After adjusting for confounding variables, we found that mild (PNI 45–50) or moderate to severe (PNI P = 0.004; OR 1.07, 95% CI 1.03–1.12, P < 0.001). In addition, we found that those with severe headache or migraine consumed less alcohol, dietary fiber, cholesterol, total folate, vitamin A, riboflavin, vitamin B6, vitamin B12, vitamin C, vitamin K, selenium, potassium, magnesium, and copper, and consumed more caffeine and theobromine than did those without severe headache or migraine. The PNI is associated with migraine prevalence, and may thus serve as a predictor of migraine risk and highlights the potential of nutrition-based strategies for migraine prevention and treatment.Keywords
Funding Information
- Sichuan Science and Technology Program (2019YFH0196)
- West China Hospital, Sichuan University (2018HXFH022)
- National Natural Science Foundation of China (81500959)
This publication has 46 references indexed in Scilit:
- The systemic inflammation-based neutrophil–lymphocyte ratio: Experience in patients with cancerCritical Reviews in Oncology/Hematology, 2013
- Sex Differences in the Prevalence, Symptoms, and Associated Features of Migraine, Probable Migraine and Other Severe Headache: Results of the American Migraine Prevalence and Prevention (AMPP) StudyHeadache: The Journal of Head and Face Pain, 2013
- Chronic Migraine Prevalence, Disability, and Sociodemographic Factors: Results From the American Migraine Prevalence and Prevention StudyHeadache: The Journal of Head and Face Pain, 2012
- A novel, externally validated inflammation-based prognostic algorithm in hepatocellular carcinoma: the prognostic nutritional index (PNI)British Journal of Cancer, 2012
- Nutritional predictors of postoperative outcome in pancreatic cancerBritish Journal of Surgery, 2010
- Vitamin effects on the immune system: vitamins A and D take centre stageNature Reviews Immunology, 2008
- Alcohol and migraine: trigger factor, consumption, mechanisms. A reviewThe Journal of Headache and Pain, 2008
- Predictive Relationship between Polyphenol and Nonfat Cocoa Solids Content of ChocolateJournal of Agricultural and Food Chemistry, 2007
- The Albumin-nutrition connection: separating myth from factNutrition, 2002
- Prognostic Nutritional Index: its usefulness as a predictor of clinical course.Journal of the American College of Nutrition, 1983