Docking alignment-3D-QSAR of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors
- 4 December 2011
- journal article
- Published by Institute of Organic Chemistry & Biochemistry in Collection of Czechoslovak Chemical Communications
- Vol. 76 (12), 1447-1469
- https://doi.org/10.1135/cccc2011070
Abstract
No abstract availableKeywords
This publication has 36 references indexed in Scilit:
- Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitorsBioorganic & Medicinal Chemistry, 2007
- Binding thermodynamics of substituted diaminopyrimidine renin inhibitorsAnalytical Biochemistry, 2007
- Aliskiren, a Novel Orally Effective Renin Inhibitor, Provides Dose-Dependent Antihypertensive Efficacy and Placebo-Like Tolerability in Hypertensive PatientsJournal of the American College of Cardiology, 2005
- The renin-angiotensin-aldosterone system and the kidney: effects on kidney diseaseThe American Journal of Medicine, 2004
- The Nonchiral Bislactim Diethoxy Ether as a Highly Stereo-Inducing Synthon for Sterically Hindered,γ-Branchedα-Amino Acids: A Practical, Large-Scale Route to an Intermediate of the Novel Renin Inhibitor AliskirenHelvetica Chimica Acta, 2003
- Structure-based design of aliskiren, a novel orally effective renin inhibitorBiochemical and Biophysical Research Communications, 2003
- Bradykinin and the pathophysiology of angioedemaInternational Immunopharmacology, 2003
- Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human reninCell Chemical Biology, 2000
- Angiotensin‐Converting Enzyme Inhibitors and Cough: A Prospective Evaluation in Hypertension and in Congestive Heart FailureThe Journal of Clinical Pharmacology, 1994
- Morphology, physiology, and molecular biology of renin secretionPhysiological Reviews, 1990