Application of Clinical Decision Support System to Assist Breast Cancer Patients with Lifestyle Modifications during the COVID-19 Pandemic: A Randomised Controlled Trial
Open Access
- 20 June 2021
- Vol. 13 (6), 2115
- https://doi.org/10.3390/nu13062115
Abstract
Clinical decision support systems (CDSS) are data aggregation tools based on computer technology that assist clinicians to promote healthy weight management and prevention of cardiovascular diseases. We carried out a randomised controlled 3-month trial to implement lifestyle modifications in breast cancer (BC) patients by means of CDSS during the COVID-19 pandemic. In total, 55 BC women at stages I-IIIA were enrolled. They were randomly assigned either to Control group, receiving general lifestyle advice (n = 28) or the CDSS group (n = 27), to whom the CDSS provided personalised dietary plans based on the Mediterranean diet (MD) together with physical activity guidelines. Food data, anthropometry, blood markers and quality of life were evaluated. At 3 months, higher adherence to MD was recorded in the CDSS group, accompanied by lower body weight (kg) and body fat mass percentage compared to control (p < 0.001). In the CDSS arm, global health/quality of life was significantly improved at the trial endpoint (p < 0.05). Fasting blood glucose and lipid levels (i.e., cholesterol, LDL, triacylglycerols) of the CDSS arm remained unchanged (p > 0.05) but were elevated in the control arm at 3 months (p < 0.05). In conclusion, CDSS could be a promising tool to assist BC patients with lifestyle modifications during the COVID-19 pandemic.This publication has 60 references indexed in Scilit:
- The Mediterranean diet improves the systemic lipid and DNA oxidative damage in metabolic syndrome individuals. A randomized, controlled, trialClinical Nutrition, 2013
- Nutrition and physical activity guidelines for cancer survivorsCA: A Cancer Journal for Clinicians, 2012
- 16. The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010British Journal of Cancer, 2011
- Validity of the Greek EORTC QLQ-C30 and QLQ-BR23 for measuring health-related quality of life in breast cancer patientsEuropean Journal of Cancer Care, 2011
- Advances in Novel Drug Delivery Strategies for Breast Cancer TherapyArtificial Cells, Blood Substitutes, and Immobilization Biotechnology, 2010
- Diet quality is directly associated with quality of life in breast cancer survivorsBreast Cancer Research and Treatment, 2006
- Disparities within traditional Mediterranean food patterns: an historical approach of the Greek dietInternational Journal of Food Sciences and Nutrition, 2006
- A validation study of the Hospital Anxiety and Depression Scale (HADS) in different groups of Dutch subjectsPsychological Medicine, 1997
- The Hospital Anxiety and Depression ScaleActa Psychiatrica Scandinavica, 1983