Typ-2-Diabetes-mellitus und Krebsrisiko
- 14 September 2021
- journal article
- editorial
- Published by Georg Thieme Verlag KG in Deutsche Medizinische Wochenschrift (1946)
- Vol. 146 (18), 1218-1225
- https://doi.org/10.1055/a-1529-4521
Abstract
Typ-2-Diabetes-mellitus-Patienten sterben heute am häufigsten an Krebs. In Dickdarm, Bauchspeicheldrüse, Gallenblase, Leber, Magen und vielen weiteren Geweben können sich T2D-assoziierte Malignomen bilden. Weitere Faktoren, wie z. B. Tabakkonsum, Bewegungsmangel und Übergewicht, erhöhen das Risiko. Menschen mit Typ-2-Diabetes sollten deshalb frühzeitig und regelmäßig zur Teilnahme an etablierten Krebsfrüherkennungsmaßnahmen eingeladen werden. Type-2-diabetes (T2D) increases the risk for several cancers and cancer has become the major cause of death of T2D-patients. T2D is causally associated with colorectal, pancreatic, gallbladder, biliary, hepatocellular, gastric, esophageal, oral, breast, endometrial, ovary, kidney and thyroid cancers as well as leukemias. When T2D goes along with tobacco smoking, alcohol use, physical inactivity, excess body weight, poor diet, familial risk or certain chronic infections, the cumulative cancer risk rises, and T2D-patients often suffer from cancer disease at younger age. T2D-patients should be encouraged to join cancer screening programmes even at younger age than the average non-diabetic population. Publication Date: 14 September 2021 (online) © 2021. Thieme. All rights reserved. Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyKeywords
This publication has 24 references indexed in Scilit:
- Early-onset gastric cancer is a distinct disease with worrisome trends and oncogenic featuresSurgery, 2019
- Emerging cancer trends among young adults in the USA: analysis of a population-based cancer registryThe Lancet Public Health, 2019
- Physical Activity and Risk of Breast Cancer: A Meta-Analysis of 38 Cohort Studies in 45 Study ReportsValue in Health, 2018
- Worldwide incidence of hepatocellular carcinoma cases attributable to major risk factorsEuropean Journal of Cancer Prevention, 2018
- Type 2 Diabetes in Relation to the Risk of Renal Cell Carcinoma Among Men and Women in Two Large Prospective Cohort StudiesDiabetes Care, 2018
- Diabetes, metabolic comorbidities, and risk of hepatocellular carcinoma: Results from two prospective cohort studiesJournal of Hepatology, 2018
- Fukuoka-Negative Branch-Duct IPMNs: When to Worry? A Study from the French Surgical Association (AFC)Annals of Surgical Oncology, 2018
- Effectiveness of the Korean National Cancer Screening Program in Reducing Gastric Cancer MortalityGastroenterology, 2017
- Evidence for DNA Damage as a Biological Link Between Diabetes and CancerChinese Medical Journal, 2015
- Diabetes and breast cancer risk: a meta-analysisBritish Journal of Cancer, 2012