Flavor Preference and Systemic Immunoglobulin Responses in E-Cigarette Users and Waterpipe and Tobacco Smokers: A Pilot Study
Open Access
- 19 January 2020
- journal article
- research article
- Published by MDPI AG in International Journal of Environmental Research and Public Health
- Vol. 17 (2), 640
- https://doi.org/10.3390/ijerph17020640
Abstract
Electronic cigarette (e-cigarette) use has had an exponential increase in popularity since the product was released to the public. Currently, there is a lack of human studies that assess different biomarker levels. This pilot study attempts to link e-cigarette and other tobacco product usage with clinical respiratory symptoms and immunoglobulin response. Subjects completed surveys in order to collect self-reported data on tobacco product flavor preferences. Along with this, plasma samples were collected to test for immunoglobulin G (IgG) and E (IgE) levels. Our pilot study’s cohort had a 47.9% flavor preference towards fruit flavors and a 63.1% preference to more sweet flavors. E-cigarette and traditional cigarette smokers were the two subject groups to report the most clinical symptoms. E-cigarette users also had a significant increase in plasma IgE levels compared to non-tobacco users 1, and dual users had a significant increase in plasma IgG compared to non-tobacco users 2, cigarette smokers, and waterpipe smokers. Our pilot study showed that users have a preference toward fruit and more sweet flavors and that e-cigarette and dual use resulted in an augmented systemic immune response.Keywords
Funding Information
- NCI (U54CA228110)
- NHLBI (1R01HL135613)
This publication has 23 references indexed in Scilit:
- Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell linesOral Oncology, 2015
- Smoking duration, respiratory symptoms, and COPD in adults aged ≥45 years with a smoking historyInternational Journal of Chronic Obstructive Pulmonary Disease, 2015
- Inhallation of e-Cigarette Cartridge Solution Aggravates Allergen-induced Airway Inflammation and Hyper-responsiveness in MiceToxicological Research, 2014
- Short-term Pulmonary Effects of Using an Electronic CigaretteSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 2012
- Smoking and Chronic Obstructive Pulmonary Disease (COPD). Parallel Epidemics of the 21st CenturyInternational Journal of Environmental Research and Public Health, 2009
- COPD and tobacco smokeMonaldi Archives for Chest Disease, 2005
- Allergy markers in respiratory epidemiologyEuropean Respiratory Journal, 2001
- Effect of low to moderate levels of smoking and alcohol consumption on serum immunoglobulin concentrations.Journal of Clinical Pathology, 1997
- Increased IgE antibody responses in rats exposed to tobacco smokeJournal of Allergy and Clinical Immunology, 1985
- The relationship of serum immunoglobulin E to cigarette smoking.Published by Elsevier BV ,1981