This article revises some of the main elements within Peirce’s general theory of signs and their relationship with discourse analysis. Our discussion focuses on the dialogues between researchers in the areas of semiotics and discourse analysis to follow up interdisciplinary studies on the processes of language signification. The article firstly relates the Peircean trivium and discourse analysis; secondly, examines Pignatari’s analysis on the relations between verbal and non-verbal codes; and, thirdly, discusses Peirce’s footprints in the development of the Linguistic Turn, especially through his influence in pthe works of Wittgenstein, Grice and Austin. The article concludes that such interdisciplinary postmodern dialogues can be used for the development of more grounded modalities of pragmatic discourse analyses.