Atrial septal defect in adulthood: a new paradigm for congenital heart disease
- 18 September 2021
- journal article
- review article
- Published by Oxford University Press (OUP) in European Heart Journal
- Vol. 43 (28), 2660-2671
- https://doi.org/10.1093/eurheartj/ehab646
Abstract
Atrial septal defects (ASDs) represent the most common congenital heart defect diagnosed in adulthood. Although considered a simple defect, challenges in optimal diagnostic and treatment options still exist due to great heterogeneity in terms of anatomy and time-related complications primarily arrhythmias, thromboembolism, right heart failure and, in a subset of patients, pulmonary arterial hypertension (PAH). Atrial septal defects call for tertiary expertise where all options may be considered, namely catheter vs. surgical closure, consideration of pre-closure ablation for patients with atrial tachycardia and suitability for closure or/and targeted therapy for patients with PAH. This review serves to update the clinician on the latest evidence, the nuances of optimal diagnostics, treatment options, and long-term follow-up care for patients with an ASD.This publication has 104 references indexed in Scilit:
- Percutaneous versus surgical closure of secundum atrial septal defects: a systematic review and meta-analysis of currently available clinical evidenceEuroIntervention, 2011
- Assessment of atrial septal defects in adults comparing cardiovascular magnetic resonance with transoesophageal echocardiographyJournal of Cardiovascular Magnetic Resonance, 2010
- 3D Echocardiography of the Atrial Septum: Anatomical Features and Landmarks for the EchocardiographerJACC: Cardiovascular Imaging, 2010
- Improved Survival Among Patients With Eisenmenger Syndrome Receiving Advanced Therapy for Pulmonary Arterial HypertensionJournal of the American College of Cardiology, 2010
- Molecular genetics of congenital atrial septal defectsClinical Research in Cardiology, 2009
- Pulmonary Arterial Hypertension in Patients With Transcatheter Closure of Secundum Atrial Septal DefectsCirculation: Cardiovascular Interventions, 2009
- Pulmonary arterial hypertension in adults born with a heart septal defect: the Euro Heart Survey on adult congenital heart diseaseHeart, 2007
- Atrial septal defect in patients ages 60 years or older: operative results and long-term postoperative follow-up.Journal of the American College of Cardiology, 1981
- Natural History and Prognosis of Atrial Septal DefectJournal of the American College of Cardiology, 1968
- Termination of Left Superior Vena Cava in Left Atrium, Atrial Septal Defect, and Absence of Coronary SinusJournal of the American College of Cardiology, 1965