Effect of Oxyjun™ on Adipose Tissue Inflammation - A Randomized, Placebo-Controlled Clinical Study
Open Access
- 26 November 2020
- journal article
- Published by Asian Research Association in International Journal of Physical Education, Fitness and Sports
- Vol. 9 (4), 37-50
- https://doi.org/10.34256/ijpefs2045
Abstract
The aim of the study was to evaluate the effect of Oxyjun™ on cardiovascular fitness of overweight individuals by reducing obesity induced systemic inflammation. Male participants between the ages of 18 - 35 years and body mass index of 25 - 34.9 kg/m2 were recruited in the study. Change in neutrophil lymphocyte ratio (NLR), high density lipoprotein (HDL-c) and quality of life using 36-item Short form survey (SF-36) was assessed over a period of 8-weeks. Results demonstrated that NLR was reduced by 0.71 in Oxyjun™ and by 0.42 in the placebo group at the end of study period. Also, within group comparison was significant for Oxyjun™ group when compared from baseline; p<0.001. Further, HDL-c levels were increased in the OxyjunTM group by 4.04 mg/dL and reduced for the placebo group by 1.22 mg/dL when compared from baseline; p=0.09. For SF-36 quality of life assessments, the health concepts of fatigue, mental health, and social function showed significant improvement and no adverse or serious adverse events were reported for both groups during the course of the study. In conclusion, Oxyjun™ when consumed for 8-weeks reduced NLR of study volunteers thereby demonstrating its potential for lowering obesity induced systemic inflammation. Oxyjun™ also increased HDL levels that could further promote cardiovascular fitness and prevent the risk of cardiovascular events.Keywords
This publication has 69 references indexed in Scilit:
- The Vascular Endothelium and Human DiseasesInternational Journal of Biological Sciences, 2013
- Effect of Different Doses of Aerobic Exercise on Total White Blood Cell (WBC) and WBC Subfraction Number in Postmenopausal Women: Results from DREWPLOS ONE, 2012
- Changes in Fitness and Fatness on the Development of Cardiovascular Disease Risk Factors: Hypertension, Metabolic Syndrome, and HypercholesterolemiaJournal of Invasive Cardiology, 2012
- Sedentary Behavior and Adiposity-Associated Inflammation: The Multi-Ethnic Study of AtherosclerosisAmerican Journal of Preventive Medicine, 2012
- Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recoveringNutrition & Metabolism, 2012
- Friend Turns Foe: Transformation of Anti-Inflammatory HDL to Proinflammatory HDL during Acute-Phase ResponseCholesterol, 2010
- Inflammation, a Link between Obesity and Cardiovascular DiseaseMediators of Inflammation, 2010
- Effect of exercise training on chronic inflammationClinica Chimica Acta; International Journal of Clinical Chemistry, 2010
- Immune and Inflammatory Mechanisms of AtherosclerosisAnnual Review of Immunology, 2009
- Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individualsJournal of the International Society of Sports Nutrition, 2008