Antitumor potential of the protein phosphatase inhibitor, cantharidin, and selected derivatives
- 9 January 2021
- journal article
- research article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry
- Vol. 32, 116012
- https://doi.org/10.1016/j.bmc.2021.116012
Abstract
No abstract availableKeywords
Funding Information
- National Cancer Institute
- National Institutes of Health
This publication has 111 references indexed in Scilit:
- Cantharidin and norcantharidin inhibit the ability of MCF-7 cells to adhere to platelets via protein kinase C pathway-dependent downregulation of α2 integrinOncology Reports, 2013
- Protein tyrosine phosphatases in health and diseaseThe FEBS Journal, 2012
- Hallmarks of Cancer: The Next GenerationCell, 2011
- Structural Basis of Serine/Threonine Phosphatase Inhibition by the Archetypal Small Molecules Cantharidin and NorcantharidinJournal of Medicinal Chemistry, 2009
- Discovery of anticancer agents of diverse natural originPure and Applied Chemistry, 2009
- DNA damage induced by novel demethylcantharidin-integrated platinum anticancer complexesBiochemical and Biophysical Research Communications, 2007
- Cantharidin-induced mitotic arrest is associated with the formation of aberrant mitotic spindles and lagging chromosomes resulting, in part, from the suppression of PP2AαMolecular Cancer Therapeutics, 2006
- Anhydride modified cantharidin analogues: synthesis, inhibition of protein phosphatases 1 and 2A and anticancer activityBioorganic & Medicinal Chemistry Letters, 2000
- Comparison of the acute toxicity of endothal and cantharidic acid on mouse liver in vivoToxicology Letters, 1987
- The Structure of Cantharidine and the Synthesis of DesoxycantharidineJournal of the American Chemical Society, 1941