Age, smoking, hypertension, and aortic aneurysm: Interactions and risks
- 6 January 2022
- journal article
- Published by Heighten Science Publications Corporation in Journal of Cardiology and Cardiovascular Medicine
- Vol. 7 (1), 001-005
- https://doi.org/10.29328/journal.jccm.1001123
Abstract
Background/Aim: Aortic aneurysm is the bulging of a weakened portion of the aorta. The aorta is the major blood vessel that feeds blood (carrying oxygen, nutrients and water) to the tissues of the body. When a portion of the wall of the aorta becomes weak, blood pushing against the vessel wall can cause it to bulge like a balloon (aneurysm) leading to aortic dissection (a tear in the wall of the aorta that can cause life-threatening bleeding or sudden death). Blood pressure is the force arterial blood exerts on the wall of the artery. When this pressure is consistently high above 140/100 mmHg it is referred to as hypertension. As an individual gets older over time, physiological functions of the body depreciate leading to some abnormalities. Smoking is the consumption of tobacco mostly by inhalation of the smoke that is produced from burning the tobacco. This review article examines the close interactions between age, smoking, hypertension and aortic aneurysm, with a view to understanding mechanisms by which these factors predispose a patient to an aortic aneurism. It is also to observe if these factors interfere with treatment and recovery from aneurysms. Conclusion: After careful review, it is observed that age and smoking are risk factors for hypertension, and together with hypertension, the three factors predispose an individual to high risk for aortic aneurysm.Keywords
This publication has 23 references indexed in Scilit:
- Exploration of the mechanisms by which 3,4-benzopyrene promotes angiotensin II-induced abdominal aortic aneurysm formation in miceJournal of Vascular Surgery, 2014
- Fruit and Vegetable Consumption With Risk of Abdominal Aortic AneurysmJournal of the American College of Cardiology, 2013
- Elevation of Plasma High-Density Lipoproteins Inhibits Development of Experimental Abdominal Aortic AneurysmsArteriosclerosis, Thrombosis, and Vascular Biology, 2012
- Cigarette smoke enhances abdominal aortic aneurysm formation in angiotensin II-treated apolipoprotein E-deficient miceToxicology Letters, 2010
- Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patientsAmerican Heart Journal, 2009
- Abdominal Aortic Aneurysms, Increasing Infrarenal Aortic Diameter, and Risk of Total Mortality and Incident Cardiovascular Disease EventsJournal of the American College of Cardiology, 2008
- Abdominal aortic aneurysm in women: Prevalence, risk factors, and implications for screeningJournal of Vascular Surgery, 2007
- Role of a Decreased Expression of the Local Renin-Angiotensin System in the Etiology of Cerebral AneurysmsJournal of the American College of Cardiology, 2003
- The Relationship Between Abdominal Aortic Aneurysm Distensibility and Serum Markers of Elastin and Collagen MetabolismEuropean Journal of Vascular and Endovascular Surgery, 2001
- Suggested standards for reporting on arterial aneurysmsJournal of Vascular Surgery, 1991