Electrochemical Anodic Synthesis and Analysis of TiO2 Nanotubes for Biomedical Applications

Abstract
Nowadays, titanium and alloy materials are encouraged for biomedical applications. Fabrication of the passive layer over the titanium materials is limited. Typically, a plain titanium sample is not suitable for bioimplant applications because the adhesion of biological elements like blood cells, tissues, and bones is poor. The use of surface-modified titanium resolves this issue. Surface modifications on titanium by electrochemical methods are simple and cost-effective. The addition of water to the ethylene-based electrolyte-enhanced the oxidation process to increase the length of the nanotubes. Surface morphological analysis shows that the length of the nanotubes has been increased, nanoindentation analysis delivers that increasing the length has been increased the hardness level, and corrosion analysis indicates that the length of nanotubes encouraged the corrosion resistance. Potentiodynamic polarization, Bode and Nyquist plots were models fit analyzed with equivalent electrical circuits. Sample cell viability was characterized with NIH-3T3 cells using an inverted microscopy analyzer.