Bodyweight-adjusted Contrast Media with Shortened Injection Duration for Step-and-Shoot Coronary Computed Tomography Angiography to Acquire Improved Image Quality
Open Access
- 23 January 2023
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Thoracic Imaging
- Vol. Publish Ah
- https://doi.org/10.1097/rti.0000000000000696
Abstract
Purpose: Shortened injection durations are not recommended in step-and-shoot coronary computed tomography angiography (CCTA). We aimed to evaluate the image quality of CCTA performed using bodyweight-adjusted iodinated contrast media (ICM) with different injection durations to generate an optimized ICM administration protocol to acquire convincible image quality in step-and-shoot CCTA. Materials and Methods: A total of 200 consecutive patients with suspected coronary artery disease (CAD) were enrolled in group A (N=50, 350 mgI/mL, bodyweight×0.8 mL/kg with a 13-s injection duration), group B (N=50, 350 mgI/mL, bodyweight×0.9 mL/kg with a 13-s injection duration), group C (N=50, 350 mgI/mL, bodyweight×0.8 mL/kg with a 12-s injection duration), and group D (N=50, 320 mgI/mL, bodyweight×0.8 mL/kg with a 13-s injection duration). Patient characteristics, ICM administration protocols, quantitative computed tomography (CT) value measurements, and qualitative image scores were analyzed and compared among the groups. Results: Groups A and D achieved the lowest ICM volume, saline volume, injection flow rate, and total iodine and iodine injection rates among the groups. All the CT values of the coronary arteries in all groups were >300 HU. All the observers’ average scores exceeded three points. In group A, the CT values showed significant positive correlation with the iodine injection rate (r=0.226, Pr=−0.004, P=0.927) and contrast-to-noise ratio (r=−0.006, P=0.893) values were not. Conclusions: Bodyweight×0.8 mL/kg with a 13-second injection duration is a comprehensive option for step-and-shoot CCTA with improved image quality, and a 350 mgI/mL iodine concentration is preferred.Keywords
This publication has 24 references indexed in Scilit:
- Cardiac-Specific Conversion Factors to Estimate Radiation Effective Dose From Dose-Length Product in Computed TomographyJACC: Cardiovascular Imaging, 2017
- High-Pitch Coronary CT Angiography at 70 kVp Adopting a Protocol of Low Injection Speed and Low Volume of Contrast MediumKorean Journal of Radiology, 2017
- Iodine Concentration and Optimization in Computed Tomography AngiographyInvestigative Radiology, 2016
- Artifacts at Cardiac CT: Physics and SolutionsRadioGraphics, 2016
- Controversies in Contrast Material–induced Acute Kidney Injury: Closing in on the Truth?Radiology, 2015
- SCCT guidelines for the interpretation and reporting of coronary CT angiography: A report of the Society of Cardiovascular Computed Tomography Guidelines CommitteeJournal of Cardiovascular Computed Tomography, 2014
- Iterative Reconstruction to Preserve Image Quality and Diagnostic Accuracy at Reduced Radiation Dose in Coronary CT AngiographyJACC: Cardiovascular Imaging, 2013
- Reduction of the total injection volume of contrast material with a short injection duration in 64-detector row CT coronary angiographyThe British Journal of Radiology, 2010
- Coronary computed tomography angiography with a consistent dose below 1 mSv using prospectively electrocardiogram-triggered high-pitch spiral acquisitionEuropean Heart Journal, 2009
- Contrast Injection Protocols for Coronary Computed Tomography Angiography Using a 64-Detector Scanner: Comparison Between Patient Weight-Adjusted- and Fixed Iodine-Dose ProtocolsInvestigative Radiology, 2008