MICRO-CT IN TISSUE ENGINEERING SCAFFOLDS DESIGNED FOR BONE REGENERATION: PRINCIPLES AND APPLICATION
Open Access
- 5 March 2018
- journal article
- research article
- Published by Institute of Rock Structure and Mechanics, AS CR in Ceramics - Silikaty
- Vol. 62 (2), 194-199
- https://doi.org/10.13168/cs.2018.0012
Abstract
Micro-CT (micro-computed tomography) is a modern preclinical imaging method allowing non-destructive visualizations and structure analysis yielding at a resolution of a few micrometres. Tissue engineering scaffolds are a promising treatment for bone defects. Micro-CT application for the evaluation of tissue engineering scaffolds for bone surgery and traumatology application is increasing, which comprises in vitro, in vivo and ex vivo studies. Micro-CT itself is not able to replace conventional approaches completely, such as scanning electron microscopy (SEM) or histological examination, but it may offer important benefits regarding non-destructive approach, direct 3D model structure analysis, and visualization and time efficacy. The overview presented herein focuses on a micro-CT application in the field of tissue engineering scaffolds aimed at bone regeneration.Keywords
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